Statistics · Updated November 9, 2026
Flu Statistics 2026
Includes CDC's 2026-27 season estimates to October 31, 2026, and final 2025-26 flu shot data
- 88statistics
- 34sources from 7 publishers
- Checkedevery figure against its original source
- FreeCSV download and ready-made citations
Compiled by the BestRatedDocs research desk from the Centers for Disease Control and Prevention (CDC), the National Center for Health Statistics (NCHS), CDC's Morbidity and Mortality Weekly Report (MMWR) and the World Health Organization (WHO) data.
Flu killed an estimated 45,000 people in the United States in the 2024-25 season, and CDC's yearly estimates since 2010 range from 6,300 to 52,000 deaths. For the 2025-26 season, CDC estimated at least 24,000 deaths and 32 million illnesses. Each figure below names who measured it, what it counts and the season.
Key findings
- 1,700,000
As of the week ending October 31, 2026, CDC estimated at least 1,700,000 flu illnesses, 25,000 hospitalizations and 1,400 deaths in the United States so far in the 2026-27 season, in its FluView report published November 6, 2026.
CDC, FluView Weekly US Influenza Surveillance Report, Week 43 (ending October 31, 2026), published November 6, 2026 · 2026-27 season (to October 31, 2026) data
- 32 million
CDC estimated that there were at least 32 million flu illnesses in the United States during the 2025-26 season, in its final in-season estimate.
CDC, FluView Weekly US Influenza Surveillance Report, Week 20 (ending May 23, 2026) · 2025-26 season data
- 6,300 to 52,000
CDC estimates that flu caused from 6,300 to 52,000 deaths a year in the United States between 2010 and 2025.
CDC, About Estimated Flu Burden · 2010-11 to 2024-25 seasons data
- 45,000
CDC estimates there were 51 million flu illnesses, 23 million medical visits, 710,000 hospitalizations and 45,000 deaths in the United States during the 2024-25 season, which CDC classified as high severity.
CDC, 2024-2025 Influenza Season Summary: Severity, Disease Burden, and Burden Prevented · 2024-25 season data
- 8 percent
On average, about 8 percent of the US population gets sick from flu each season, with a range of 3 percent to 11 percent depending on the season, according to a 2018 CDC study cited by CDC.
CDC, About Influenza · 2010-11 to 2015-16 seasons data
- 298
CDC's pediatric mortality surveillance counts 298 flu-associated deaths among U.S. children under 18 in the 2024-25 season, the highest season total since reporting began in 2004-05 (BestRatedDocs calculation from CDC's season totals).
CDC FluView Interactive, Influenza-Associated Pediatric Mortality · 2024-25 season data
- 89%
Of the children who died of flu in the 2024-25 season and were old enough to be vaccinated, 89% were not fully vaccinated, according to CDC (based on 208 children with known vaccination status).
CDC, MMWR: Influenza-Associated Pediatric Deaths, United States, 2024-25 Influenza Season (Reinhart et al.) · 2024-25 season data
- 43.8%
CDC estimates that 43.8% of people in the United States aged 6 months and older got a flu vaccine in the 2025-26 season, unchanged from the 2024-25 season.
CDC FluVaxView, Flu Vaccination Coverage, United States, 2025-26 Influenza Season · 2025-26 season data
- 12,000
CDC estimates that flu vaccination prevented 12,000 flu-related deaths in the United States during the 2024-25 season.
CDC, 2024-2025 Influenza Season Summary: Severity, Disease Burden, and Burden Prevented · 2024-25 season data
- 290,000 to 650,000
Seasonal flu causes an estimated 290,000 to 650,000 respiratory deaths worldwide each year, according to the World Health Organization.
World Health Organization (WHO), Influenza (seasonal) fact sheet · Annual estimate data
- 74
There have been 74 reported human cases of A(H5) bird flu in the United States since February 2024, according to the CDC (as of November 5, 2026).
CDC, A(H5) Bird Flu: Current Situation (updated November 5, 2026) · February 2024 to November 2026 data
How Bad Is the 2026-27 Flu Season So Far?
As of the week ending October 31, 2026, CDC estimated at least 1,700,000 flu illnesses and 1,400 deaths in the new season. Activity is rising and is higher than usual for the time of year, and so far the season is mostly A(H1N1). CDC's preliminary severity assessment rated it low for all ages at that point.
- 1,700,000
As of the week ending October 31, 2026, CDC estimated at least 1,700,000 flu illnesses, 25,000 hospitalizations and 1,400 deaths in the United States so far in the 2026-27 season, in its FluView report published November 6, 2026.
CDC, FluView Weekly US Influenza Surveillance Report, Week 43 (ending October 31, 2026), published November 6, 2026 · 2026-27 season (to October 31, 2026) data [1]
- 9.1%
In the week ending October 31, 2026, 9.1% of respiratory specimens tested by US clinical laboratories were positive for flu, according to CDC.
CDC, FluView Weekly US Influenza Surveillance Report, Week 43 (ending October 31, 2026), published November 6, 2026 · 2026-27 season (to October 31, 2026) data [1]
- 8,396
US hospitals reported 8,396 lab-confirmed flu hospital admissions in the week ending October 31, 2026, a rate of 2.5 per 100,000 people and up from the week before, according to CDC's National Healthcare Safety Network data.
CDC, FluView Weekly US Influenza Surveillance Report, Week 43 (ending October 31, 2026), published November 6, 2026 · 2026-27 season (to October 31, 2026) data [1]
- 3
Three flu-associated deaths among US children in the 2026-27 season had been reported to CDC as of the week ending October 31, 2026.
CDC, FluView Weekly US Influenza Surveillance Report, Week 43 (ending October 31, 2026), published November 6, 2026 · 2026-27 season (to October 31, 2026) data [1]
These are early, cumulative minimums from CDC's weekly FluView report and will rise every week until the season ends. CDC notes that an earlier rise in activity does not necessarily mean a higher peak or a more severe season. We update this section as new weekly reports come out.
How Many People Got the Flu in the 2025-26 Season?
CDC's last in-season estimate for 2025-26, published in May 2026, put the season at no fewer than 32 million illnesses and 24,000 deaths. It was an A(H3N2) season driven largely by a drifted strain called subclade K.
- 32 million
CDC estimated that there were at least 32 million flu illnesses in the United States during the 2025-26 season, in its final in-season estimate.
CDC, FluView Weekly US Influenza Surveillance Report, Week 20 (ending May 23, 2026) · 2025-26 season data [2]
- 390,000
CDC estimated at least 390,000 flu hospitalizations in the United States during the 2025-26 season.
CDC, FluView Weekly US Influenza Surveillance Report, Week 20 (ending May 23, 2026) · 2025-26 season data [2]
- 24,000
CDC estimated at least 24,000 flu deaths in the United States during the 2025-26 season.
CDC, FluView Weekly US Influenza Surveillance Report, Week 20 (ending May 23, 2026) · 2025-26 season data [2]
- moderate
CDC's in-season severity framework classified the 2025-26 flu season as moderate across all ages, while children 0-17 years had a high-severity season.
CDC, FluView Weekly US Influenza Surveillance Report, Week 20 (ending May 23, 2026) · 2025-26 season data [2]
- 93%
Among A(H3N2) viruses genetically characterized in the 2025-26 season through February 2026, 93% were subclade K, a drifted strain that differs from the vaccine virus, CDC reported in MMWR.
CDC, MMWR: Interim Estimates of 2025-26 Seasonal Influenza Vaccine Effectiveness · 2025-26 season data [4]
- 90.0 per 100,000
The cumulative lab-confirmed flu hospitalization rate in CDC's FluSurv-NET network reached 90.0 per 100,000 people for the 2025-26 season (October 1, 2025 to September 26, 2026).
CDC, FluView Weekly US Influenza Surveillance Report, Week 38 (ending September 26, 2026) · 2025-26 season data [5]
CDC's in-season numbers are cumulative minimums ('at least') and are not directly comparable with the end-of-season point estimates for past seasons. CDC stopped weekly burden estimates for 2025-26 in late spring, as it does every year, and publishes a full-season estimate later.
Flu Illnesses, Hospitalizations and Deaths by Year
CDC's modeled estimates show how much flu seasons vary: from 9.4 million to 51 million illnesses a year since 2010. The 2024-25 season had the most illnesses of any season CDC has estimated since 2010-11 and matched 2017-18 for hospitalizations.
Source: CDC, Flu Disease Burden: Past Seasons, rounded estimates (all ages) CSV. Chart: BestRatedDocs, free to reuse with a link to this page.
Show chart data
| 2010-11 | 38,000 |
|---|---|
| 2011-12 | 13,000 |
| 2012-13 | 43,000 |
| 2013-14 | 38,000 |
| 2014-15 | 51,000 |
| 2015-16 | 22,000 |
| 2016-17 | 38,000 |
| 2017-18 | 52,000 |
| 2018-19 | 32,000 |
| 2019-20 | 26,000 |
| 2021-22 | 6,300 |
| 2022-23 | 25,000 |
| 2023-24 | 26,000 |
| 2024-25 | 45,000 |
- 6,300 to 52,000
CDC estimates that flu caused from 6,300 to 52,000 deaths a year in the United States between 2010 and 2025.
CDC, About Estimated Flu Burden · 2010-11 to 2024-25 seasons data [6]
- 9.4 million to 51 million
Flu caused an estimated 9.4 million to 51 million illnesses and 120,000 to 710,000 hospitalizations a year in the United States between 2010 and 2025, according to CDC.
CDC, About Estimated Flu Burden · 2010-11 to 2024-25 seasons data [6]
- 45,000
CDC estimates there were 51 million flu illnesses, 23 million medical visits, 710,000 hospitalizations and 45,000 deaths in the United States during the 2024-25 season, which CDC classified as high severity.
CDC, 2024-2025 Influenza Season Summary: Severity, Disease Burden, and Burden Prevented · 2024-25 season data [7]
- 38,000 to 110,000
CDC's 95% uncertainty interval for flu deaths in the 2024-25 season runs from 38,000 to 110,000 deaths in the United States.
CDC, Flu Disease Burden: Past Seasons, rounded estimates (all ages) CSV · 2024-25 season data [8]
- 51 million
The 51 million estimated flu illnesses in the 2024-25 season were the most of any US season since at least 2010-11, according to CDC.
CDC, 2024-2025 Influenza Season Summary: Severity, Disease Burden, and Burden Prevented · 2024-25 season data [7]
- 52,000
The 2017-18 season was the deadliest since 2010 in CDC's estimates, with 52,000 US flu deaths (95% interval 36,000 to 99,000) and 710,000 hospitalizations.
CDC, Flu Disease Burden: Past Seasons, rounded estimates (all ages) CSV · 2017-18 season data [8]
- 6,300
The 2021-22 season had the fewest estimated US flu deaths of any season CDC has estimated since 2010, at 6,300, with 120,000 hospitalizations, according to CDC.
CDC, Flu Disease Burden: Past Seasons, rounded estimates (all ages) CSV · 2021-22 season data [8]
- 9.4 million
The 2011-12 season had the fewest estimated US flu illnesses of any season CDC has estimated since 2010, at 9.4 million.
CDC, Flu Disease Burden: Past Seasons, rounded estimates (all ages) CSV · 2011-12 season data [8]
| Season | Illnesses | Medical visits | Hospitalizations | Deaths | Deaths range |
|---|---|---|---|---|---|
| 2010-11 | 23 million | 11 million | 310,000 | 38,000 | 22,000 to 150,000 |
| 2011-12 | 9.4 million | 4.4 million | 140,000 | 13,000 | 7,200 to 36,000 |
| 2012-13 | 34 million | 16 million | 580,000 | 43,000 | 25,000 to 120,000 |
| 2013-14 | 30 million | 13 million | 350,000 | 38,000 | 23,000 to 100,000 |
| 2014-15 | 30 million | 14 million | 590,000 | 51,000 | 34,000 to 100,000 |
| 2015-16 | 24 million | 11 million | 280,000 | 22,000 | 17,000 to 38,000 |
| 2016-17 | 29 million | 14 million | 500,000 | 38,000 | 27,000 to 61,000 |
| 2017-18 | 41 million | 19 million | 710,000 | 52,000 | 36,000 to 99,000 |
| 2018-19 | 29 million | 14 million | 400,000 | 32,000 | 21,000 to 79,000 |
| 2019-20 | 34 million | 15 million | 380,000 | 26,000 | 18,000 to 88,000 |
| 2020-21 | Not estimated | Not estimated | Not estimated | Not estimated | Not estimated |
| 2021-22 | 11 million | 5.1 million | 120,000 | 6,300 | 4,000 to 16,000 |
| 2022-23 | 29 million | 13 million | 340,000 | 25,000 | 18,000 to 48,000 |
| 2023-24 | 37 million | 17 million | 430,000 | 26,000 | 22,000 to 61,000 |
| 2024-25 | 51 million | 23 million | 710,000 | 45,000 | 38,000 to 110,000 |
Source: CDC, Flu Disease Burden: Past Seasons, rounded estimates (all ages) CSV
These are CDC model estimates with 95% uncertainty intervals, not counts. Estimates for 2024-25 are still preliminary and will change as more data arrive. CDC did not estimate the 2020-21 season because flu activity was minimal.
What Percentage of People Get the Flu Each Year?
On average about 8 percent of Americans get sick with flu each season, with a range of 3 to 11 percent. Children are the most likely to catch it.
- 8 percent
On average, about 8 percent of the US population gets sick from flu each season, with a range of 3 percent to 11 percent depending on the season, according to a 2018 CDC study cited by CDC.
CDC, About Influenza · 2010-11 to 2015-16 seasons data [9]
- 9.3%
Median seasonal flu incidence was 9.3% for children 0-17, 8.8% for adults 18-64 and 3.9% for adults 65 and older, according to CDC.
CDC, About Influenza · 2010-11 to 2015-16 seasons data [9]
- twice
US children younger than 18 are more than twice as likely as adults 65 and older to get symptomatic flu in a season, according to CDC.
CDC, About Influenza · 2010-11 to 2015-16 seasons data [9]
- 8.3%
The median statistical estimate of symptomatic flu incidence among all ages in the United States was 8.3% per season (95% CI 7.3% to 9.7%), ranging from 3.0% to 11.3%, in a 2018 CDC study in Clinical Infectious Diseases.
Tokars et al., Seasonal Incidence of Symptomatic Influenza in the United States, Clinical Infectious Diseases (2018) · 2010-11 to 2015-16 seasons data [10]
The 8 percent average comes from a 2018 CDC study of the 2010-11 to 2015-16 seasons and counts symptomatic illness only, including people who never saw a doctor. Our 2024-25 percentages are calculated from CDC's modeled illness rates for a single, unusually large season.
Who Dies From the Flu? Deaths and Hospitalizations by Age
Older adults account for most flu deaths in nearly every season. In the 2024-25 season, people 65 and older made up 71% of CDC's estimated flu deaths.
Source: CDC, Flu Disease Burden: Past Seasons, estimates by age group CSV. Chart: BestRatedDocs, free to reuse with a link to this page.
Show chart data
| Ages 0-4 | 433 |
|---|---|
| Ages 5-17 | 357 |
| Ages 18-49 | 2,929 |
| Ages 50-64 | 9,485 |
| Ages 65+ | 31,734 |
- 31,734
CDC's preliminary model estimates 31,734 flu deaths among US adults 65 and older in the 2024-25 season, a death rate of 51.9 per 100,000.
CDC, Flu Disease Burden: Past Seasons, estimates by age group CSV · 2024-25 season data [11]
- 666.3 per 100,000
Adults 65 and older had an estimated flu hospitalization rate of 666.3 per 100,000 in the 2024-25 season, the highest of any age group in CDC's estimates.
CDC, Flu Disease Burden: Past Seasons, estimates by age group CSV · 2024-25 season data [11]
Age figures here are CDC model estimates for the 2024-25 season, the newest season with an age breakdown; they are still preliminary. Children rarely die of flu compared with older adults, but CDC also tracks reported child deaths separately. CDC has published two ranges for the 65-and-older share of flu deaths. Its current page on flu and people 65 and older (updated September 2026) says 70 to 85 percent in recent US seasons, and that is the range we use. An archived CDC page on the 2009 H1N1 pandemic (last updated 2019) says about 70 to 90 percent for typical seasonal epidemics, an older and wider range written to contrast with the pandemic. The 2024-25 estimate of 71% falls inside both.
How Many Children Die From the Flu?
Flu deaths in children under 18 have been nationally notifiable in the United States since 2004, so CDC counts every lab-confirmed case reported by state health departments. The 2024-25 season set the record, with 298 deaths reported so far.
Source: CDC FluView Interactive, Influenza-Associated Pediatric Mortality (data as of week ending October 31, 2026). Chart: BestRatedDocs, free to reuse with a link to this page.
Show chart data
| 2004-05 | 47 |
|---|---|
| 2005-06 | 46 |
| 2006-07 | 77 |
| 2007-08 | 88 |
| 2008-09 | 137 |
| 2009-10 | 288 |
| 2010-11 | 124 |
| 2011-12 | 37 |
| 2012-13 | 171 |
| 2013-14 | 111 |
| 2014-15 | 148 |
| 2015-16 | 95 |
| 2016-17 | 110 |
| 2017-18 | 188 |
| 2018-19 | 145 |
| 2019-20 | 199 |
| 2020-21 | 1 |
| 2021-22 | 49 |
| 2022-23 | 187 |
| 2023-24 | 211 |
| 2024-25 | 298 |
| 2025-26 | 202 |
- 298
CDC's pediatric mortality surveillance counts 298 flu-associated deaths among U.S. children under 18 in the 2024-25 season, the highest season total since reporting began in 2004-05 (BestRatedDocs calculation from CDC's season totals).
CDC FluView Interactive, Influenza-Associated Pediatric Mortality · 2024-25 season data [13]
- 202
CDC has received reports of 202 flu-associated deaths among U.S. children in the 2025-26 season, as of the week ending October 31, 2026.
CDC FluView, Weekly US Influenza Surveillance Report, Week 43 ending October 31, 2026 · 2025-26 season data [1]
- 288
During the 2009-10 H1N1 pandemic season, 288 flu-associated deaths among U.S. children were reported to CDC.
CDC, MMWR: Influenza-Associated Pediatric Deaths, United States, 2024-25 Influenza Season (Reinhart et al.) · 2009-10 season data [14]
- 89%
Of the children who died of flu in the 2024-25 season and were old enough to be vaccinated, 89% were not fully vaccinated, according to CDC (based on 208 children with known vaccination status).
CDC, MMWR: Influenza-Associated Pediatric Deaths, United States, 2024-25 Influenza Season (Reinhart et al.) · 2024-25 season data [14]
- 85%
About 85% of the children who died of flu in the 2025-26 season were not fully vaccinated, among those eligible for vaccination with known status, CDC reported in May 2026.
CDC FluView, Weekly US Influenza Surveillance Report, Week 20 ending May 23, 2026 · 2025-26 season data [2]
- 56%
In the 2024-25 season, 56% of U.S. children who died of flu had at least one underlying medical condition, CDC found.
CDC, MMWR: Influenza-Associated Pediatric Deaths, United States, 2024-25 Influenza Season (Reinhart et al.) · 2024-25 season data [14]
- 109
CDC identified 109 cases of flu-associated encephalopathy, a severe brain complication, in U.S. children during the 2024-25 season; 55% of the children had been previously healthy and 19% died.
CDC, MMWR: Pediatric Influenza-Associated Encephalopathy and Acute Necrotizing Encephalopathy, United States, 2024-25 Influenza Season · 2024-25 season data [15]
- 790
Allowing for children who were never tested, CDC estimates there were 790 flu-related deaths among U.S. children younger than 18 in the 2024-25 season, a modeled figure separate from the reported count.
CDC, 2024-2025 Influenza Season Summary: Severity, Disease Burden, and Burden Prevented · 2024-25 season data [7]
Reported deaths are a count of lab-confirmed cases and are known to undercount, because not every child who dies is tested for flu. CDC's modeled estimate for 2024-25 (790 deaths) is a separate measure and should not be compared directly with the reported counts. Counts for recent seasons keep rising as late reports arrive: the 2024-25 total was 280 in September 2025, 297 in April 2026 and 298 in October 2026, which is now above the 288 deaths recorded in the 2009-10 pandemic season.
How Many Flu Deaths Are on Death Certificates?
Death certificates recorded 6,512 influenza deaths and 48,139 influenza and pneumonia deaths in the United States in 2024. Rates vary more than threefold between states.
- 48,139
48,139 deaths in the United States were attributed to influenza and pneumonia on death certificates in 2024, a rate of 14.2 per 100,000, according to NCHS.
CDC NCHS, FastStats: Influenza · 2024 data [16]
- 6,512
Death certificates listed influenza itself as the cause of 6,512 US deaths in 2024, a rate of 1.9 per 100,000, according to NCHS.
CDC NCHS, FastStats: Influenza · 2024 data [16]
- 19.1
Mississippi had the highest age-adjusted influenza and pneumonia death rate of any state in 2024, at 19.1 per 100,000 (701 deaths), according to NCHS.
CDC NCHS, Stats of the States: Influenza and Pneumonia Mortality · 2024 data [17]
- 5.9
Colorado had the lowest age-adjusted influenza and pneumonia death rate of any state in 2024, at 5.9 per 100,000 (381 deaths), according to NCHS.
CDC NCHS, Stats of the States: Influenza and Pneumonia Mortality · 2024 data [17]
- 5,535
California recorded the most influenza and pneumonia deaths of any state in 2024, at 5,535, followed by New York at 4,153, according to NCHS.
CDC NCHS, Stats of the States: Influenza and Pneumonia Mortality · 2024 data [17]
| State | Death rate per 100,000 | Deaths |
|---|---|---|
| Alabama | 14.5 | 956 |
| Alaska | 10.4 | 70 |
| Arizona | 10 | 1,009 |
| Arkansas | 17.1 | 670 |
| California | 11.6 | 5,535 |
| Colorado | 5.9 | 381 |
| Connecticut | 13.9 | 716 |
| Delaware | 11.8 | 173 |
| District of Columbia | 6.8 | 48 |
| Florida | 8.5 | 3,093 |
| Georgia | 10.4 | 1,297 |
| Hawaii | 10.6 | 250 |
| Idaho | 7.3 | 171 |
| Illinois | 11.8 | 1,936 |
| Indiana | 11.2 | 953 |
| Iowa | 12 | 533 |
| Kansas | 12.3 | 459 |
| Kentucky | 13.1 | 740 |
| Louisiana | 11.4 | 634 |
| Maine | 10.1 | 222 |
| Maryland | 9.3 | 727 |
| Massachusetts | 11.1 | 1,058 |
| Michigan | 10.5 | 1,405 |
| Minnesota | 6.6 | 490 |
| Mississippi | 19.1 | 701 |
| Missouri | 12.9 | 1,045 |
| Montana | 8.9 | 135 |
| Nebraska | 12.1 | 296 |
| Nevada | 13.9 | 556 |
| New Hampshire | 8.6 | 177 |
| New Jersey | 10 | 1,235 |
| New Mexico | 14.2 | 390 |
| New York | 15 | 4,153 |
| North Carolina | 12.6 | 1,704 |
| North Dakota | 9.6 | 101 |
| Ohio | 11.5 | 1,790 |
| Oklahoma | 14.1 | 679 |
| Oregon | 6.1 | 346 |
| Pennsylvania | 12.2 | 2,289 |
| Rhode Island | 9 | 141 |
| South Carolina | 9.4 | 665 |
| South Dakota | 13.4 | 160 |
| Tennessee | 15.5 | 1,360 |
| Texas | 10.6 | 3,326 |
| Utah | 10.1 | 299 |
| Vermont | 8.6 | 81 |
| Virginia | 9.6 | 1,052 |
| Washington | 8.1 | 762 |
| West Virginia | 18.4 | 481 |
| Wisconsin | 7.9 | 616 |
| Wyoming | 10 | 73 |
Source: CDC NCHS, Stats of the States: Influenza and Pneumonia Mortality
These are counts of death certificates (calendar year 2024, NCHS), a different measure from CDC's modeled seasonal estimates, and the two should not be compared directly. CDC says flu is underreported on death certificates: 'patients aren't always tested for seasonal influenza virus infection, particularly older adults who are at greatest risk of seasonal flu complications and death,' and 'only counting deaths where flu was recorded on a death certificate would be a gross underestimation of flu's true impact.' Most influenza and pneumonia deaths are from pneumonia. State rates are age-adjusted; the national FastStats rate is deaths per 100,000 population.
What Percentage of People Get a Flu Shot?
Fewer than half of Americans got a flu vaccine in the 2025-26 season. Coverage among children rose slightly for the first time since the COVID-19 pandemic but remains far below pre-pandemic levels, and every group is below the Healthy People 2030 target of 70%.
Source: CDC, Influenza Vaccination Coverage for All Ages (6+ Months), data.cdc.gov (NIS-Flu). Chart: BestRatedDocs, free to reuse with a link to this page.
Show chart data
| 2015-16 | 59.3% |
|---|---|
| 2016-17 | 59% |
| 2017-18 | 57.8% |
| 2018-19 | 62.5% |
| 2019-20 | 63.7% |
| 2020-21 | 58.6% |
| 2021-22 | 57.8% |
| 2022-23 | 57.4% |
| 2023-24 | 55.4% |
| 2024-25 | 50.2% |
| 2025-26 | 51.4% |
- 43.8%
CDC estimates that 43.8% of people in the United States aged 6 months and older got a flu vaccine in the 2025-26 season, unchanged from the 2024-25 season.
CDC FluVaxView, Flu Vaccination Coverage, United States, 2025-26 Influenza Season · 2025-26 season data [18]
- 51.4%
In the 2025-26 season, 51.4% of U.S. children aged 6 months through 17 years got a flu vaccine, the first increase since before the COVID-19 pandemic, according to CDC.
CDC FluVaxView, Flu Vaccination Coverage, United States, 2025-26 Influenza Season · 2025-26 season data [18]
- 41.6%
CDC estimates that 41.6% of U.S. adults aged 18 and older got a flu vaccine in the 2025-26 season, similar to 41.9% in the 2024-25 season.
CDC FluVaxView, Flu Vaccination Coverage, United States, 2025-26 Influenza Season · 2025-26 season data [18]
- 64.4%
Among U.S. adults aged 65 and older, 64.4% got a flu vaccine in the 2025-26 season, below the Healthy People 2030 goal of 70%, according to CDC.
CDC FluVaxView, Flu Vaccination Coverage, United States, 2025-26 Influenza Season · 2025-26 season data [18]
- 31.4%
Adults aged 18 to 49 had the lowest flu vaccination coverage of any age group in the 2025-26 season, at 31.4%, according to CDC's BRFSS estimates.
CDC FluVaxView, Flu Vaccination Coverage by Age Group, Adults, United States, 2025-26 Season (Excel table) · 2025-26 season data [19]
- 135.6 million
Manufacturers and distributors had shipped 135.6 million doses of flu vaccine in the United States for the 2025-26 season as of March 7, 2026, according to CDC.
CDC FluVaxView, Weekly Flu Vaccination Dashboard · 2025-26 season data [20]
- 36.42 million
An estimated 36.42 million flu vaccine doses were given to adults in U.S. retail pharmacies in the 2025-26 season through April 25, 2026, about 1.3 million fewer than at the same point in 2024-25, based on IQVIA claims data reported by CDC.
CDC FluVaxView, Weekly Flu Vaccination Dashboard (IQVIA data) · 2025-26 season data [20]
- 76.3%
In the 2024-25 season, 76.3% of U.S. health care personnel reported getting a flu vaccine, in a CDC internet panel survey of 2,650 workers.
CDC, MMWR: Influenza and COVID-19 Vaccination Coverage Among Health Care Personnel, United States, 2024-25 Respiratory Virus Season · 2024-25 season data [21]
| Age group | 2024-25 | 2025-26 |
|---|---|---|
| Everyone 6 months and older | 43.8% | 43.8% |
| Children 6 months to 17 years | 50.2% | 51.4% |
| 6 months to 4 years | 57.5% | 60.0% |
| 5 to 12 years | 51.3% | 52.7% |
| 13 to 17 years | 43.4% | 43.3% |
| Adults 18 and older | 41.9% | 41.6% |
| 18 to 49 years | 31.2% | 31.4% |
| 50 to 64 years | 42.1% | 40.1% |
| 65 and older | 63.8% | 64.4% |
Source: CDC, Influenza Vaccination Coverage for All Ages (6+ Months), data.cdc.gov (NIS-Flu and BRFSS)
Final coverage comes from two surveys: the National Immunization Survey-Flu for children (parent report) and the Behavioral Risk Factor Surveillance System for adults (self-report). CDC notes that the children's survey has overestimated coverage by roughly 6 to 10 percentage points. Final estimates differ from the in-season weekly dashboard, which uses a different adult survey and method. Doses distributed count vaccine shipped, not people vaccinated.
How Effective Is the Flu Vaccine?
In CDC's vaccine effectiveness studies, the flu vaccine has cut the risk of a flu-related doctor visit by between 19% and 60% in each season since 2009-10. How well it works depends on how closely the vaccine matches the viruses that circulate.
- 36%
CDC's preliminary estimate puts flu vaccine effectiveness at 36% (95% CI 33 to 39) in the 2025-26 season, based on 135,422 patients across eight states.
CDC, Past Seasons' Vaccine Effectiveness Estimates · 2025-26 season data [23]
- 56%
In the 2024-25 season, the flu vaccine was an estimated 56% effective (95% CI 54 to 58) at preventing medically attended flu, CDC's preliminary estimate shows, the joint second-highest since 2009-10.
CDC, Past Seasons' Vaccine Effectiveness Estimates · 2024-25 season data [23]
- 41%
In CDC's interim 2025-26 estimates, the flu vaccine was 41% effective against flu hospitalization in children and adolescents under 18, and 38% to 41% effective against flu outpatient visits.
CDC, MMWR: Interim Estimates of 2025-26 Seasonal Influenza Vaccine Effectiveness, United States, September 2025-February 2026 (Maloney et al.) · 2025-26 season data [4]
- 30%
Among U.S. adults aged 18 and older, CDC's interim 2025-26 estimates put flu vaccine effectiveness at 30% against flu hospitalization and 22% to 34% against flu outpatient visits.
CDC, MMWR: Interim Estimates of 2025-26 Seasonal Influenza Vaccine Effectiveness, United States, September 2025-February 2026 (Maloney et al.) · 2025-26 season data [4]
| Season | Adjusted VE | 95% CI |
|---|---|---|
| 2009-10 | 56% | 23 to 75 |
| 2010-11 | 60% | 53 to 66 |
| 2011-12 | 47% | 36 to 56 |
| 2012-13 | 49% | 43 to 55 |
| 2013-14 | 52% | 44 to 59 |
| 2014-15 | 19% | 10 to 27 |
| 2015-16 | 48% | 41 to 55 |
| 2016-17 | 40% | 32 to 46 |
| 2017-18 | 38% | 31 to 43 |
| 2018-19 | 29% | 21 to 35 |
| 2019-20 | 39% | 32 to 44 |
| 2020-21 | Not estimated | n/a |
| 2021-22 | 36% | 21 to 48 |
| 2022-23 | 30% | -9 to 54 |
| 2023-24 | 44% | 36 to 51 |
| 2024-25 (preliminary) | 56% | 54 to 58 |
| 2025-26 (preliminary) | 36% | 33 to 39 |
Vaccine effectiveness (VE) is the percentage reduction in risk of a lab-confirmed flu outcome among vaccinated people compared with unvaccinated people, measured with a test-negative design. The season table shows VE against medically attended flu (outpatient, urgent care and emergency department visits) from CDC's networks; VE against hospitalization is reported separately. Estimates for 2024-25 and 2025-26 are preliminary, and VE was not estimated for 2020-21 because almost no flu circulated.
How Many Illnesses Does the Flu Vaccine Prevent?
CDC models how much flu vaccination prevented each season from that season's flu burden, vaccine coverage and vaccine effectiveness. In the high-severity 2024-25 season, the newest with an estimate, vaccination prevented an estimated 10 million illnesses and 12,000 deaths.
- 10 million
CDC estimates that flu vaccination prevented 10 million flu-related illnesses in the United States during the 2024-25 season.
CDC, 2024-2025 Influenza Season Summary: Severity, Disease Burden, and Burden Prevented · 2024-25 season data [7]
- 5 million
Flu vaccination prevented an estimated 5 million flu-related medical visits in the United States during the 2024-25 season, according to CDC.
CDC, 2024-2025 Influenza Season Summary: Severity, Disease Burden, and Burden Prevented · 2024-25 season data [7]
- 180,000
Flu vaccination prevented an estimated 180,000 flu-related hospitalizations in the United States during the 2024-25 season, according to CDC.
CDC, 2024-2025 Influenza Season Summary: Severity, Disease Burden, and Burden Prevented · 2024-25 season data [7]
- 12,000
CDC estimates that flu vaccination prevented 12,000 flu-related deaths in the United States during the 2024-25 season.
CDC, 2024-2025 Influenza Season Summary: Severity, Disease Burden, and Burden Prevented · 2024-25 season data [7]
- 81%
Most (81%) of the flu deaths prevented by vaccination in the 2024-25 season were among adults aged 65 and older, CDC estimates.
CDC, 2024-2025 Influenza Season Summary: Severity, Disease Burden, and Burden Prevented · 2024-25 season data [7]
- 49%
Adults aged 18 to 49 accounted for the largest share (49%) of flu illnesses prevented by vaccination in the 2024-25 season, CDC estimates.
CDC, 2024-2025 Influenza Season Summary: Severity, Disease Burden, and Burden Prevented · 2024-25 season data [7]
| Outcome | Occurred | Prevented by vaccination |
|---|---|---|
| Illnesses | 51 million | 10 million |
| Medical visits | 23 million | 5 million |
| Hospitalizations | 710,000 | 180,000 |
| Deaths | 45,000 | 12,000 |
Source: CDC, 2024-2025 Influenza Season Summary: Severity, Disease Burden, and Burden Prevented
These are model estimates, not counts, and CDC will revise the 2024-25 figures as final data arrive (expected in 2027). CDC corrected the illnesses-prevented figure to 10 million on March 12, 2026. Prevented burden depends on how many people were vaccinated and how well the vaccine matched, so it varies widely between seasons.
How Many People Get the Flu Worldwide?
The World Health Organization estimates the global toll of seasonal flu each year. These are modeled estimates, since most countries do not test every case.
- around a billion
Seasonal flu causes around a billion cases worldwide every year, according to the World Health Organization's influenza fact sheet.
World Health Organization (WHO), Influenza (seasonal) fact sheet · Annual estimate data [24]
- 3 to 5 million
Of those flu cases, 3 to 5 million each year worldwide are severe illness, according to the World Health Organization.
World Health Organization (WHO), Influenza (seasonal) fact sheet · Annual estimate data [24]
- 290,000 to 650,000
Seasonal flu causes an estimated 290,000 to 650,000 respiratory deaths worldwide each year, according to the World Health Organization.
World Health Organization (WHO), Influenza (seasonal) fact sheet · Annual estimate data [24]
- 99%
An estimated 99% of deaths in children under 5 with flu-related lower respiratory tract infections happen in developing countries, according to the World Health Organization.
World Health Organization (WHO), Influenza (seasonal) fact sheet · Annual estimate data [24]
- 166 institutions across 136
WHO's Global Influenza Surveillance and Response System, which tracks flu viruses to pick each year's vaccine strains, currently comprises 166 institutions across 136 WHO member states, according to the World Health Organization.
World Health Organization (WHO), Global Influenza Surveillance and Response System (GISRS) · 2026 data [25]
- since 1952
The World Health Organization has run global flu surveillance through its Global Influenza Surveillance and Response System since 1952.
World Health Organization (WHO), Global Influenza Surveillance and Response System (GISRS) · 1952 to 2026 data [25]
WHO's death range counts respiratory deaths only, so deaths from flu-triggered heart attacks or strokes are not included. WHO figures are global and are not comparable with CDC's U.S. burden estimates.
How Much Does the Flu Cost?
Flu costs the U.S. billions of dollars a year in medical care and lost work. The two most cited estimates come from peer-reviewed studies in the journal Vaccine, and they measure cost in different ways.
- $11.2 billion
Seasonal flu costs the U.S. healthcare system and society an estimated $11.2 billion a year on average (range $6.3 billion to $25.3 billion), based on the 2015 U.S. population, according to a 2018 study by Putri and colleagues in the journal Vaccine.
Putri et al., Economic burden of seasonal influenza in the United States, Vaccine (2018) · 2015 U.S. population data [26]
- $3.2 billion
Direct medical costs of seasonal flu in the U.S. are estimated at $3.2 billion a year (range $1.5 billion to $11.7 billion), based on the 2015 U.S. population, according to a 2018 study by Putri and colleagues in the journal Vaccine.
Putri et al., Economic burden of seasonal influenza in the United States, Vaccine (2018) · 2015 U.S. population data [26]
- $8.0 billion
Indirect costs of seasonal flu in the U.S., mostly paid work missed, are estimated at $8.0 billion a year (range $4.8 billion to $13.6 billion), based on the 2015 U.S. population, according to a 2018 study by Putri and colleagues in the journal Vaccine.
Putri et al., Economic burden of seasonal influenza in the United States, Vaccine (2018) · 2015 U.S. population data [26]
- 20.1 million
Seasonal flu causes an estimated 20.1 million days of lost productivity in the U.S. each year on average, based on the 2015 U.S. population, according to a 2018 study by Putri and colleagues in the journal Vaccine.
Putri et al., Economic burden of seasonal influenza in the United States, Vaccine (2018) · 2015 U.S. population data [26]
- $87.1 billion
An older 2007 estimate by Molinari and colleagues in the journal Vaccine put the total annual economic burden of U.S. flu epidemics at $87.1 billion in 2003 dollars, a figure that includes a statistical value for lives lost.
Molinari et al., The annual impact of seasonal influenza in the US: measuring disease burden and costs, Vaccine (2007) · 2003 U.S. population, 2003 dollars data [27]
- 31.4 million outpatient visits
Flu epidemics led to an average of 31.4 million outpatient visits and 3.1 million hospitalized days a year in the U.S., based on the 2003 population, according to an older 2007 estimate by Molinari and colleagues in the journal Vaccine.
Molinari et al., The annual impact of seasonal influenza in the US: measuring disease burden and costs, Vaccine (2007) · 2003 U.S. population data [27]
The 2018 study (Putri et al.) counts medical costs and paid work missed, applied to the 2015 U.S. population. The older 2007 study (Molinari et al.) used 2003 dollars and also put a statistical value on lives lost, which is why its total is far higher. The two totals should not be compared as a trend.
The Deadliest Flu Pandemics in History
Four flu pandemics have struck in the past century: 1918, 1957, 1968 and 2009. The 1918 pandemic was by far the deadliest.
Source: CDC, What CDC Is Doing (Pandemic Flu) for 1918, and CDC's archived pandemic pages for 1957, 1968 and 2009. Chart: BestRatedDocs, free to reuse with a link to this page.
Show chart data
| 1918 (H1N1) | 675,000 |
|---|---|
| 1957 (H2N2) | 116,000 |
| 1968 (H3N2) | 100,000 |
| 2009 (H1N1) | 12,469 |
- 50 to 100 million
The 1918-19 flu pandemic was the most severe in the past century, killing 675,000 Americans and 50 to 100 million people worldwide, according to the CDC.
CDC, What CDC Is Doing (Pandemic Flu) · 1918-19 data [28]
- about 500 million
During the 1918 flu pandemic, about 500 million people, or one-third of the world's population, are estimated to have been infected, according to the CDC.
CDC, 1918 Pandemic (H1N1 virus) (archived page) · 1918-19 data [29]
- 1.1 million
The 1957-58 H2N2 flu pandemic killed an estimated 1.1 million people worldwide and 116,000 in the United States, according to the CDC.
CDC, 1957-1958 Pandemic (H2N2 virus) (archived page) · 1957-58 data [30]
- 1 million
The 1968 H3N2 flu pandemic killed an estimated 1 million people worldwide and about 100,000 in the United States, most of them aged 65 and older, according to the CDC.
CDC, 1968 Pandemic (H3N2 virus) (archived page) · 1968 data [31]
- 60.8 million
From April 12, 2009 to April 10, 2010, the 2009 H1N1 pandemic caused an estimated 60.8 million cases (range 43.3 million to 89.3 million), 274,304 hospitalizations and 12,469 deaths in the United States, according to the CDC.
CDC, 2009 H1N1 Pandemic (H1N1pdm09 virus) (archived page) · April 2009 to April 2010 data [32]
- 151,700 to 575,400
An estimated 151,700 to 575,400 people worldwide died from the 2009 H1N1 pandemic virus during its first year of circulation, according to the CDC.
CDC, 2009 H1N1 Pandemic (H1N1pdm09 virus) (archived page) · 2009-10 data [32]
- 80 percent
Globally, 80 percent of deaths linked to the 2009 H1N1 pandemic virus are estimated to have occurred in people younger than 65, according to the CDC. The same archived 2019 page says about 70 percent to 90 percent of deaths in typical seasonal epidemics occur in people 65 and older, an older, wider range than the 70 percent to 85 percent CDC now gives for recent US seasons.
CDC, 2009 H1N1 Pandemic (H1N1pdm09 virus) (archived page) · 2009-10 data [32]
| Pandemic | Virus | Est. deaths worldwide | Est. U.S. deaths |
|---|---|---|---|
| 1918 | H1N1 | 50 million to 100 million | 675,000 |
| 1957-58 | H2N2 | 1.1 million | 116,000 |
| 1968 | H3N2 | 1 million | 100,000 |
| 2009 | H1N1 | 151,700 to 575,400 (first year) | 12,469 |
Source: CDC, What CDC Is Doing (Pandemic Flu) and CDC archived pandemic pages
Pandemic death counts are historical estimates and vary by study. CDC's current page gives 50 to 100 million deaths worldwide for 1918; its older, archived pandemic pages say at least 50 million. Worldwide figures for 1957, 1968 and 2009 come from CDC's archived pandemic pages, which CDC no longer updates.
Bird Flu (H5N1) Cases in People
H5 bird flu has spread widely in wild birds, poultry and U.S. dairy cows, with sporadic infections in people who work with animals. CDC rates the current public health risk as low and has found no person-to-person spread.
Source: WHO, Cumulative number of confirmed human cases for avian influenza A(H5N1) reported to WHO, 2003-2026. Chart: BestRatedDocs, free to reuse with a link to this page.
Show chart data
| 2003-2009 | 468 |
|---|---|
| 2010-2014 | 233 |
| 2015-2019 | 160 |
| 2020-2024 | 102 |
| 2025 | 31 |
| 2026 (to Oct 7) | 11 |
- 74
There have been 74 reported human cases of A(H5) bird flu in the United States since February 2024, according to the CDC (as of November 5, 2026).
CDC, A(H5) Bird Flu: Current Situation (updated November 5, 2026) · February 2024 to November 2026 data [33]
- 44
Of the 74 U.S. human A(H5) bird flu cases since 2024, 44 followed exposure to dairy cattle herds, 24 to poultry farms and culling operations, 3 to other animals and 3 had an unknown source, according to the CDC (as of November 5, 2026).
CDC, A(H5) Bird Flu: Current Situation (updated November 5, 2026) · 2024 to November 2026 data [33]
- 3 deaths
A(H5) bird flu has caused 3 deaths in the United States since 2024, according to the CDC (as of November 5, 2026), which reports no known person-to-person spread.
CDC, A(H5) Bird Flu: Current Situation (updated November 5, 2026) · 2024 to November 2026 data [33]
- 1,005
From 2003 to 7 October 2026, 1,005 laboratory-confirmed human A(H5N1) bird flu cases, including 479 deaths, were reported to the World Health Organization worldwide.
World Health Organization (WHO), Cumulative number of confirmed human cases for avian influenza A(H5N1) reported to WHO, 2003-2026 · 2003 to 7 October 2026 data [34]
- 48%
About 48% of the human A(H5N1) bird flu cases reported to the World Health Organization from 2003 to 7 October 2026 were fatal (BestRatedDocs calculation from WHO data).
BestRatedDocs calculation from WHO, Cumulative number of confirmed human cases for avian influenza A(H5N1) reported to WHO, 2003-2026 · 2003 to 7 October 2026 data [34]
CDC's U.S. count covers all A(H5) cases since 2024, confirmed and probable. WHO's worldwide table counts laboratory-confirmed A(H5N1) cases since 2003 (for the U.S. in 2024-2025 it also includes cases reported as A(H5)), so its U.S. figures (71 cases, 1 death) differ from CDC's (74 cases, 3 deaths as of November 5, 2026). The case fatality ratio reflects severe cases that get tested and reported; mild infections are likely missed.
Methodology
Most U.S. figures on this page come from the Centers for Disease Control and Prevention (CDC). CDC does not count every flu case or death. It estimates the season's illnesses, medical visits, hospitalizations and deaths with a model built on lab-confirmed hospitalizations in its FluSurv-NET network, adjusted for people who were never tested. Each estimate has a 95% uncertainty interval, which we give where CDC publishes it. Estimates for 2023-24 and later seasons are preliminary and CDC revises them.
We keep three kinds of flu death figures apart because they measure different things. CDC's modeled estimates (for example, 45,000 deaths in 2024-25) try to capture every death flu caused. Death certificate counts from the National Center for Health Statistics (NCHS) are by calendar year and only include deaths where flu or pneumonia was written down, so they run far lower. Reported child deaths are a count of lab-confirmed cases notified to CDC, and CDC's separate model estimate for children is higher.
The 2025-26 burden figures are CDC's last in-season estimates, published in May 2026. CDC labels them as minimums ('at least'), so they should not be compared directly with the end-of-season estimates for past seasons. Vaccination coverage for 2025-26 is CDC's final estimate, from the National Immunization Survey-Flu for children and the Behavioral Risk Factor Surveillance System for adults, released in October 2026. Vaccine effectiveness comes from CDC's test-negative studies and is preliminary for 2024-25 and 2025-26.
Global figures come from the World Health Organization's seasonal influenza fact sheet and its cumulative table of human H5N1 cases. Historic pandemic figures are CDC estimates, some from CDC's archived pandemic pages, and vary between studies. The cost figures come from two peer-reviewed studies in the journal Vaccine, published in 2007 and 2018, which used different methods and years. Figures marked 'BestRatedDocs calculation' were worked out by us from the source's own numbers, and the arithmetic is in the CSV download.
Spot an error or a newer figure? Tell us and we will correct the page and note the change.
Cite this page
Free to quote, chart or link in articles, reports and coursework. Please credit the original source for each figure and link to this page as the compilation.
BestRatedDocs. (2026, November 9). Flu Statistics 2026. https://bestrateddocs.com/flu-statistics/
"Flu Statistics 2026." BestRatedDocs, 9 Nov. 2026, bestrateddocs.com/flu-statistics.
BestRatedDocs. "Flu Statistics 2026." Last modified November 9, 2026. https://bestrateddocs.com/flu-statistics/
<a href="https://bestrateddocs.com/flu-statistics/">Flu Statistics 2026</a> (BestRatedDocs)
Frequently asked questions
How many people die from the flu each year?
CDC estimates that flu caused from 6,300 to 52,000 deaths a year in the United States between 2010 and 2025. The deadliest season in that span was 2017-18, with an estimated 52,000 deaths, and the 2024-25 season caused an estimated 45,000. These are model estimates. Death certificates list far fewer: influenza itself was named as the cause of 6,512 U.S. deaths in 2024, according to NCHS, because many people who die of flu complications are never tested.
How many people died from the flu in the 2025-26 season?
In its final in-season estimate, CDC estimated at least 24,000 flu deaths, 390,000 hospitalizations and 32 million illnesses in the 2025-26 season. These are minimums, and CDC publishes a full-season estimate later. CDC classified the season as moderate overall and high severity for children, and 202 child deaths had been reported as of October 31, 2026. For the new 2026-27 season, CDC estimated at least 1,400 deaths and 1,700,000 illnesses as of the week ending October 31, 2026.
How many people get the flu each year?
On average, about 8 percent of the U.S. population gets sick from flu each season, with a range of 3 percent to 11 percent, according to a CDC study of the 2010-11 to 2015-16 seasons. CDC's yearly estimates since 2010 range from 9.4 million to 51 million illnesses. The 2024-25 season, at 51 million, had the most of any season since at least 2010-11. Worldwide, WHO counts around a billion flu cases a year.
How many children die from the flu each year?
CDC's count of reported flu deaths in children reached 298 in the 2024-25 season, the highest season total since reporting began in 2004-05. The 2025-26 season had 202 reported child deaths as of October 31, 2026. Of the children who died in 2024-25 and were old enough to be vaccinated, 89% were not fully vaccinated. Because many children are never tested, CDC estimates the true 2024-25 toll at 790.
What percentage of people get a flu shot?
CDC estimates that 43.8% of people aged 6 months and older got a flu vaccine in the 2025-26 season. Coverage was 51.4% for children, 41.6% for adults 18 and older and 64.4% for adults 65 and older. Adults aged 18 to 49 had the lowest coverage, at 31.4%.
How effective is the flu vaccine?
Effectiveness changes every season with how well the vaccine matches the viruses that circulate. CDC's preliminary estimates put it at 56% in the 2024-25 season and 36% in the 2025-26 season, when a drifted H3N2 strain called subclade K dominated. CDC estimates that vaccination prevented 10 million illnesses, 180,000 hospitalizations and 12,000 deaths in the 2024-25 season.
How many people die from the flu worldwide?
Seasonal flu causes an estimated 290,000 to 650,000 respiratory deaths worldwide each year, according to the World Health Organization, out of around a billion cases and 3 to 5 million cases of severe illness. The deadliest flu pandemic on record, in 1918-19, killed 50 to 100 million people worldwide and 675,000 Americans, according to CDC.
Who is most likely to die from the flu?
Older adults. CDC says people 65 and older account for between 70 percent and 85 percent of seasonal flu deaths in recent years. In the 2024-25 season they made up an estimated 71% of flu deaths and 57% of flu hospitalizations. Children get sick more often: median seasonal flu incidence was 9.3% for children, against 3.9% for adults 65 and older.
Sources
- CDC, FluView Weekly US Influenza Surveillance Report, Week 43 (ending October 31, 2026), published November 6, 2026 cdc.gov
- CDC, FluView Weekly US Influenza Surveillance Report, Week 20 (ending May 23, 2026) cdc.gov
- CDC, FluView Weekly US Influenza Surveillance Report, Week 39 (ending October 3, 2026) cdc.gov
- CDC, MMWR: Interim Estimates of 2025-26 Seasonal Influenza Vaccine Effectiveness cdc.gov
- CDC, FluView Weekly US Influenza Surveillance Report, Week 38 (ending September 26, 2026) cdc.gov
- CDC, About Estimated Flu Burden cdc.gov
- CDC, 2024-2025 Influenza Season Summary: Severity, Disease Burden, and Burden Prevented cdc.gov
- CDC, Flu Disease Burden: Past Seasons, rounded estimates (all ages) CSV cdc.gov
- CDC, About Influenza cdc.gov
- Tokars et al., Seasonal Incidence of Symptomatic Influenza in the United States, Clinical Infectious Diseases (2018) pubmed.ncbi.nlm.nih.gov
- CDC, Flu Disease Burden: Past Seasons, estimates by age group CSV (BestRatedDocs calculation) cdc.gov
- CDC, Flu and People 65 Years and Older cdc.gov
- CDC FluView Interactive, Influenza-Associated Pediatric Mortality gis.cdc.gov
- CDC, MMWR: Influenza-Associated Pediatric Deaths, United States, 2024-25 Influenza Season (Reinhart et al.) cdc.gov
- CDC, MMWR: Pediatric Influenza-Associated Encephalopathy and Acute Necrotizing Encephalopathy, United States, 2024-25 Influenza Season cdc.gov
- CDC NCHS, FastStats: Influenza cdc.gov
- CDC NCHS, Stats of the States: Influenza and Pneumonia Mortality cdc.gov
- CDC FluVaxView, Flu Vaccination Coverage, United States, 2025-26 Influenza Season cdc.gov
- CDC FluVaxView, Flu Vaccination Coverage by Age Group, Adults, United States, 2025-26 Season (Excel table) cdc.gov
- CDC FluVaxView, Weekly Flu Vaccination Dashboard cdc.gov
- CDC, MMWR: Influenza and COVID-19 Vaccination Coverage Among Health Care Personnel, United States, 2024-25 Respiratory Virus Season cdc.gov
- CDC, Influenza Vaccination Coverage for All Ages (6+ Months), data.cdc.gov (NIS-Flu) data.cdc.gov
- CDC, Past Seasons' Vaccine Effectiveness Estimates cdc.gov
- World Health Organization (WHO), Influenza (seasonal) fact sheet who.int
- World Health Organization (WHO), Global Influenza Surveillance and Response System (GISRS) who.int
- Putri et al., Economic burden of seasonal influenza in the United States, Vaccine (2018) pubmed.ncbi.nlm.nih.gov
- Molinari et al., The annual impact of seasonal influenza in the US: measuring disease burden and costs, Vaccine (2007) pubmed.ncbi.nlm.nih.gov
- CDC, What CDC Is Doing (Pandemic Flu) cdc.gov
- CDC, 1918 Pandemic (H1N1 virus) (archived page) archive.cdc.gov
- CDC, 1957-1958 Pandemic (H2N2 virus) (archived page) archive.cdc.gov
- CDC, 1968 Pandemic (H3N2 virus) (archived page) archive.cdc.gov
- CDC, 2009 H1N1 Pandemic (H1N1pdm09 virus) (archived page) archive.cdc.gov
- CDC, A(H5) Bird Flu: Current Situation (updated November 5, 2026) cdc.gov
- World Health Organization (WHO), Cumulative number of confirmed human cases for avian influenza A(H5N1) reported to WHO, 2003-2026 cdn.who.int