About Penetrex
Penetrex is a topical joint and muscle care brand from Biomax Health Products, Inc. The company's own site says Biomax was founded in 1998, is the exclusive worldwide distributor of Penetrex, and has its cream made in the USA, with a Southern California laboratory named on its company page. The flagship daily cream is a non-NSAID formula built around arnica montana, MSM, vitamin B6 and boswellia, and the brand describes it as a fast-absorbing, non-greasy cream that does not stain clothing.
Beyond the daily cream, Penetrex sells a roll-on gel, a pump lotion, menthol and warming creams, morning and nighttime creams, and a joint, muscle and nerve support supplement. Our reviews return to the 4 oz Joint & Muscle Care Cream for a practical reason: it absorbs without leaving residue, carries a near-neutral scent, and the 4 oz tube gives enough cream for daily massage, including when a partner or caregiver is applying it to a back or shoulder.
Brand website: penetrex.com
What Penetrex makes
Penetrex's range runs wider than the products we review. The lines we know best from our own testing are marked with a star:
Daily Joint & Muscle Care Cream
the flagship non-NSAID cream, sold in 2 oz and 4 oz sizes — featured on BestRatedDocs
Daily Care Gel Roll-On
a 3 oz roll-on gel format made for carrying in a bag
Daily Care Lotion Pump
an 8 oz pump lotion version of the daily formula
Advanced Pain Relief Cream with Menthol
a 2 oz cream with 5% menthol for people who want a cooling sensation
Morning and Nighttime Creams
2 oz creams scented with lemon balm and peppermint for the morning and lavender essential oil for the evening
Joint, Muscle & Nerve Support Supplement
a 60 count oral supplement that sits alongside the topical range
Why we recognized Penetrex
The BestRatedDocs Top Brand recognition isn't paid for and can't be applied for. We award it to the brands whose products consistently stand out in our category reviews. Penetrex earned it on the strength of the products below, evaluated the same way every product on this site is: assessed against clinical criteria, verified specifications, and real-world user outcomes, and judged on merit.
Penetrex products we rated highly
Penetrex Joint & Muscle Care Cream 4 oz
A daily massage cream built around arnica montana, MSM, vitamin B6 and boswellia. The texture is non-greasy and absorbs without residue, which suits caregiver-applied massage on a partner's back or shoulder. The scent is near-neutral and easy to live with in shared spaces, and the 4 oz tube holds enough for daily use over several weeks.
Read the 7 Best Pain Relief Creams of 2026 guide →What earned Penetrex the recognition
- A top pick in our pain relief cream review for daily massage use
- A botanical formula built around arnica montana, MSM, vitamin B6 and boswellia
- A non-greasy cream that absorbs without residue, so it suits hands-on massage
- A near-neutral scent that stays out of the way at home and around other people
- A 4 oz tube sized for daily application over several weeks